Found 40 matching trials
Effects of Endotoxin in Normal Human Volunteers
PHASE1Bacterial infections can progress to a life-threatening illness called sept...
Location
National Institutes of Health Clinical Center, 9000 Rockville Pike
PET Imaging of Endotoxin-induced iNOS Activation
PHASE1The overall purpose of this research is to gain understanding of the basic ...
Location
Washington University School of Medicne
Nasal Inflammation Following Endotoxin Challenge in Patients With Asthma
PHASE1A phase I clinical research study aimed at determining mechanisms that regu...
Location
National Jewish Health
A Study of Inhalation of 20,000 EU CCRE in Normal Volunteers Compared to Allergic Asthmatic Individuals
PHASE1This will be a single center, open label study comparing baseline character...
Location
UNC Center for Environmental Medicine, Asthma and Lung Biology
In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human Endotoxemia - VECTOR II
PHASE3Excessive inflammation is associated with tissue damage caused by over-acti...
Location
Radboud University
Inhalation of 20,000 Endotoxin Units(EU) of Clinical Center Reference Endotoxin in Healthy Volunteers
PHASE1The purpose of this study is to determine the inflammatory response to 20,0...
Assessing NOS Uptake With PET Imaging in Lung Inflammation
EARLY_PHASE1The purpose of this study is to learn more about the basic responses of the...
Location
Washington University School of Medicine / Barnes-Jewish Hospital
Effect of Retaron® on Oxygen Induced Retinal Vasoconstriction in LPS Induced Inflammatory Model in Humans
NAOxidative stress has been implicated to play a pathogenic role in many dise...
Location
Department of clinical Pharmacology, Medical University of Vienna
Study of the Efficacy and Safety of Intravenous vs Oral Acetaminophen for Treatment of Fever in Healthy Adult Males
PHASE3To assess the rapidity of onset of antipyretic effect and the efficacy and ...
Location
New Orleans Center for Clinical Research-Knoxville
The Effects of Hydrocortisone in Endotoxemia in Normal Volunteers
PHASE1Corticosteroids are substances produced by the adrenal gland to help the bo...